Laboratory testing for cobalamin deficiency in megaloblastic anemia

Status of laboratory testing in the diagnosis of megaloblastic anemia.

By John Lindenbaum W HAT WAS ONCE relatively straightforward, seems lately to have become more confusing. In the past decade, new opportunities and new problems in the diagnostic approach to the patient with a possible megaboblastic anemia have appeared with the development and nearly ubiquitous use of new technobogies-electronic determination of the mean corpuscubar volume (MCV) and an apparen...

Megaloblastic anemia of pregnancy: characteristics of pure megaloblastic anemia and megaloblastic anemia associated with iron deficiency.

LTHOUGH megaboblastic anemia of pregnancy is considered mainly as a folic acid deficiency anemia, since this vitamin induces remission in most cases, its mechanism of production is still obscure. Dietary deficiency has been claimed to be the principal cause. However, this anemia has been observed in well-to-do women whose diet was satisfactory. Some other factors such as gastrointestinal upset,...

Megaloblastic Anemia in Pregnancy

MegalobJastic Anemia in Pregnancy Megaloblastic Anemia is one of The Rather Common Diseases of Pregnant Women Caused by Folic acid Defi­ciency The Disease Might Be Hazardous To affected Mo­thers and also Could be Fatal for foetus too.  Megaloblastic Pregnant Women Will have Signs and Symptoms of This Disease mostly after 29th. Week of pregnancy.  Adequate amount of Folate Will prevent Compli...

Megaloblastic anaemia, cobalamin, and folate.

Developments relating to cobalamin and folate are reviewed. Current work on the relations between these two coenzymes are discussed, particularly those that have emerged in studies using nitrous oxide, which inactivates cobalamin.

Macrocytic Anemia: Megaloblastic Anemia (Vitamin B 12-Deficiency and Folate Deficiency)